Laser & Optoelectronics Progress, Volume. 60, Issue 15, 1528002(2023)

A Novel Colorimetric Glucose Biosensor Based on Graphene Oxide-Gold Nanoparticles-Glucose Oxidase Composites

Bing Xu1,2、*, Yan Li1,2, Zhihui Luo1,2, and Jianglou Huang1,2
Author Affiliations
  • 1College of Science, China Three Gorges University, Yichang 443002, Hubei, China
  • 2Hubei Engineering Research Center of Weak Magnetic-Filed Detection, Yichang 443002, Hubei, China
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    Figures & Tables(14)
    Preparation principle of GO-AuNPs-GOD complex
    Principle of the colorimetric method for glucose solution detection
    Characterization of GO-AuNPs composite nanoparticles. (a) UV absorption spectra; (b)(c) TEM image
    Survival rate of cells cultured with different mass concentrations of GO-AuNPs composite nanoparticles for different periods
    Characterization of GO-AuNPs-GOD composites nanoparticles. (a) UV absorption spectra; (b) Raman spectra
    Zeta potential test diagram of complex
    Effect of particle size on sensor
    Effect of Au /GO volume ratio on sensor performance
    Effect of GOD mass concentration on sensor performance
    Effect of pH on sensor performance
    Sensitivity of the sensor. (a) Absorption spectra at different glucose mass concentrations; (b) relationship between the change of absorption wavelength and glucose mass concentration
    Selectivity of sensor
    • Table 1. Compared with similar sensors

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      Table 1. Compared with similar sensors

      MaterialMechanismLinear rangeSensitivityReference
      GO-AuNPs-GODColorimetric0-1.6 mg/mL14.4 nm/(mg/mL)This work
      Ag@AuTNPsColorimetric0-30 mmol·L-10.00325 A800/mmol·L-134
      GO-AuNPs-GOD-FiberSPR0-11 mmol·L-11.06 nm/mmol·L-135
    • Table 2. Detection of glucose in SBF

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      Table 2. Detection of glucose in SBF

      Sample No.Mass concentration of added glucose /(mg·mL-1Mass concentration of detected glucose /(mg·mL-1aRecovery /%
      10.500.51102.00
      20.900.8998.89
      31.301.2495.38
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    Bing Xu, Yan Li, Zhihui Luo, Jianglou Huang. A Novel Colorimetric Glucose Biosensor Based on Graphene Oxide-Gold Nanoparticles-Glucose Oxidase Composites[J]. Laser & Optoelectronics Progress, 2023, 60(15): 1528002

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    Paper Information

    Category: Remote Sensing and Sensors

    Received: Dec. 28, 2022

    Accepted: Feb. 17, 2023

    Published Online: Aug. 11, 2023

    The Author Email: Xu Bing (xbwhut2018@163.com)

    DOI:10.3788/LOP223419

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