Laser & Optoelectronics Progress, Volume. 58, Issue 1, 117001(2021)

Study on Synovial Arthritis Based on Surface-Enhanced Raman Scattering Spectroscopy

Dong Xianhu1, Tang Shuzhen1, Chen Sunyu2、*, Xu Jianshu1, Lin Yamin1, Gao Siqi1, Zhong Haoran1, Lin Tingting1, and Gao Jiamin1
Author Affiliations
  • 1MOE of Key Laboratory of Opto-Electronic Science and Technology for Medicine, Fujian Provincial Key Laboratory for Photonics Technology, College of Photonic and Electronic Engineering of Fujian Normal University, Fuzhou, Fujian 350007, China
  • 2Department of Orthopaedics, Affiliated Fuzhou the Second Hospital of Xiamen University, Fuzhou, Fujian 350007, China
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    Figures & Tables(4)
    SERS average spectra and different spectra of joint fluid from arthritis patients(n=18) and normal people(n=15)
    Posterior probability and ROC curves.(a) Posterior probability scatter of SERS spectra of joint fluid from arthritis patients and normal people based on PCA-LDA analysis and cross-validation method; (b) ROC curves under different identification thresholds
    Three-dimensional scatter plot of SERS spectra of joint fluid from arthritis patients (dot) and normal people (pentagram) based on PCA-LDA analysis and cross-validation method
    • Table 1. Raman peak positions and tentative assignments[19-27]

      View table

      Table 1. Raman peak positions and tentative assignments[19-27]

      Peak position /cm-1Tentative assignment
      477Polysaccharides
      490Glycogen
      596Phosphatidylinositol
      640C-S stretching & C-C twisting of proteins tyrosine
      722DNA
      1071Glucose
      1439δ (CH2)(lipids)
      1576Guanine(N3)
      1645Amide I
      1676Amide I
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    Dong Xianhu, Tang Shuzhen, Chen Sunyu, Xu Jianshu, Lin Yamin, Gao Siqi, Zhong Haoran, Lin Tingting, Gao Jiamin. Study on Synovial Arthritis Based on Surface-Enhanced Raman Scattering Spectroscopy[J]. Laser & Optoelectronics Progress, 2021, 58(1): 117001

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Mar. 20, 2020

    Accepted: --

    Published Online: Jan. 28, 2021

    The Author Email: Sunyu Chen (hunson2009@163.com)

    DOI:10.3788/LOP202158.0117001

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