Journal of Inorganic Materials, Volume. 37, Issue 11, 1225(2022)

Cobalt-incorporated Chlorapatite: Preparation by Molten Salt Method, Anti-oxidation and Cytocompatibility

Chaoqin SHU1...2, Min ZHU1,* and Yufang ZHU2,* |Show fewer author(s)
Author Affiliations
  • 11. School of Materials and Chemistry, University of Shanghai for Science and Technology, Shanghai 200093, China
  • 22. State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
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    Figures & Tables(13)
    XRD patterns of Co-MS-TCP powders prepared by molten salt method with different holding time
    SEM images of β-TCP powders before and after molten salt treatment with different holding time
    H2O2 scavenging effect of (A) MS-TCP and (B) Co-MS-TCP powders prepared by molten salt method with different holding time
    XRD patterns of Co-MS-TCP powders prepared by molten salt method with different cobalt salt additions
    SEM images of Co-MS-TCP powders prepared by molten salt method with different cobalt salt additions
    Contents and valence state of cobalt in Co-MS-TCP on H2O2 scavenging ability
    Releases of (A) Ca, (B) P and (C) Co ions from β-TCP, MS-TCP and 3% Co-MS-TCP powders in Tris-HCl buffer
    SEM images of (A1, A2) β-TCP, (B1, B2) MS-TCP and (C1, C2) 3% Co-MS-TCP after soaking in SBF for 7 d and (D) their corresponding FT-IR spectra
    Cell viabilities of MS-TCP and 3% Co-MS-TCP powders with different concentrations on (A) cartilage cells and (B) bone marrow mesenchymal stem cells
    Images of intracellular ROS staining fluorescence in cartilage cells stimulated by H2O2 treatment with powders (A) Blank, (B) β-TCP, (C) MS-TCP, (D) 3% Co-MS-TCP and (E) corresponding fluorescence intensity statistics
    Images of intracellular ROS staining fluorescence in bone marrow mesenchymal stem cells stimulated by H2O2 treatment with powders (A) Blank, (B) β-TCP, (C) MS-TCP, (D) 3% Co-MS-TCP and (E) Corresponding fluorescence intensity statistics.
    Calcein AM and PI fluorescence images of cartilage cells treated with different powders((A) Blank; (B) β-TCP; (C) MS-TCP; (D) 3% Co-MS-TCP; (A1-D1) Cells without H2O2 stimulation; (A2-D2) Cells stimulated with H2O2 showing live (green) and death (red) cells)
    Calcein AM and PI fluorescence images of bone marrow mesenchymal stem cells treated with powders (A) Blank; (B) β-TCP; (C) MS-TCP; (D) 3% Co-MS-TCP; (A1-D1) Cells without H2O2 stimulation; (A2-D2) Cells stimulated with H2O2 showing live (green) and death (red) cells
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    Chaoqin SHU, Min ZHU, Yufang ZHU. Cobalt-incorporated Chlorapatite: Preparation by Molten Salt Method, Anti-oxidation and Cytocompatibility[J]. Journal of Inorganic Materials, 2022, 37(11): 1225

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    Paper Information

    Category: RESEARCH ARTICLE

    Received: Jan. 21, 2022

    Accepted: --

    Published Online: Jan. 12, 2023

    The Author Email: ZHU Min (mzhu@usst.edu.cn), ZHU Yufang (zjf2412@163.com)

    DOI:10.15541/jim20220040

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