Journal of Innovative Optical Health Sciences, Volume. 8, Issue 2, 1550003(2015)
A saccharides sensor developed by symmetrical optical waveguide-based surface plasmon resonance
We proposed a new saccharides sensor developed by symmetrical optical waveguide (SOW)- based surface plasmon resonance (SPR). This unique MgF2/Au/MgF2/Analyte film structure results in longer surface plasmon wave (SPW) propagation lengths and depths, leading to an increment of resolution. In this paper, we managed to decorate the dielectric interface (MgF2 layer) by depositing a thin polydopamine film as surface-adherent that provides a platform for secondary reactions with the probe molecule. 3-Aminophenylboronic acid (3-PBA) is chosen to be the saccharides sense probe molecule in the present work. The aqueous humor of Diabetes and Cataract patient whose blood glucose level is normal are analyzed and the results demonstrated that this sensor shows great potential in monitoring the blood sugar and can be adapted in the field of biological monitoring in the future.
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Ang Li, Zhouyi Guo, Qing Peng, Chan Du, Xida Han, Le Liu, Jun Guo, Yonghong He, Yanhong Ji. A saccharides sensor developed by symmetrical optical waveguide-based surface plasmon resonance[J]. Journal of Innovative Optical Health Sciences, 2015, 8(2): 1550003
Received: Nov. 5, 2013
Accepted: Mar. 16, 2014
Published Online: Jan. 10, 2019
The Author Email: He Yonghong (heyh@sz.tsinghua.edu.cn)