Journal of Innovative Optical Health Sciences, Volume. 4, Issue 2, 97(2011)

OPTICAL MEASUREMENT OF PHOTOSENSITIZER CONCENTRATION IN VIVO

MARTIN R. AUSTWICK1... JOSEPHINE H. WOODHAMS1,*, VADZIM CHALAU1, CHARLES A. MOSSE1, CAROLINE ELIOT1, LAURENCE LOVAT1, ALEXANDER J. MACROBERT1, IRVING J. BIGIO2 and STEPHEN G. BOWN1 |Show fewer author(s)
Author Affiliations
  • 1National Medical Laser Centre Charles Bell House, 67-73 Riding House Street University College London London W1W 7EJ, UK
  • 2Boston University, BME, 44 Cummington Street Boston, MA 02215, USA
  • show less
    References(30)

    [1] [1] J. R. Mourant, T. M. Johnson, G. Los, I. J. Bigio, "Non-invasive measurement of chemotherapy drug concentrations in tissue: Preliminary demonstrations of in vivo measurements," Phys. Med. Biol. 44, 1397-1417 (1999).

    [2] [2] S. C. Kanick, J. L. Eiseman, R. S. Parker, "Pharmacokinetic modeling of motexafin gadolinium disposition in mouse tissues using optical pharmacokinetic system measurements," Photodiagnosis. Photodyn. Ther. 5, 276-284 (2008).

    [3] [3] A. Johansson, J. Svensson, N. Bendsoe, K. Svanberg, E. Alexandratou, M. Kyriazi, D. Yova, S. Grafe, T. Trebst, S. Andersson-Engels, "Fluorescence and absorption assessment of a lipid mTHPC formulation following topical application in a nonmelanotic skin tumor model," J. Biomed. Opt. 12, 034026 (2007).

    [4] [4] K. S. Johnson, D. W. Chicken, D. C. Pickard, A. C. Lee, G. Briggs, M. Falzon, I. J. Bigio, M. R. Keshtgar, S. G. Bown, "Elastic scattering spectroscopy for intraoperative determination of sentinel lymph node status in the breast," J. Biomed. Opt. 9, 1122-1128 (2004).

    [5] [5] L. B. Lovat, K. Johnson, G. D. Mackenzie, B. R. Clark, M. R. Novelli, S. Davies, M. O'Donovan, C. Selvasekar, S.M.Thorpe,D. Pickard,R. Fitzgerald, T. Fearn, I. J. Bigio, S. G. Bown, "Elastic scattering spectroscopy accurately detects high grade dysplasia and cancer in Barrett's oesophagus," Gut 55, 1078-1083 (2006).

    [6] [6] A. Sharwani, W. Jerjes, V. Salih, B. Swinson, I. J. Bigio, M. El-Maaytah, C. Hopper, "Assessment of oral premalignancy using elastic scattering spectroscopy," Oral Oncol. 42, 343-349 (2006).

    [7] [7] R. Reif, O. A'amar, I. J. Bigio, "Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media," Appl. Opt. 46, 7317-7328 (2007).

    [8] [8] R. A. Weersink, J. E. Hayward, K. R. Diamond, M. S. Patterson, "Accuracy of noninvasive in vivo measurements of photosensitizer uptake based on a diffusion model of reflectance spectroscopy," Photochem. Photobiol. 66, 326-335 (1997).

    [9] [9] A. Kienle, M. S. Patterson, "Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium," J. Opt. Soc. Am. A Opt. Image Sci. Vis. 14, 246-254 (1997).

    [10] [10] R. M. Doornbos, R. Lang, M. C. Aalders, F. W. Cross, H. J. Sterenborg, "The determination of in vivo human tissue optical properties and absolute chromophore concentrations using spatially resolved steady-state diffuse reflectance spectroscopy," Phys. Med. Biol. 44, 967-981 (1999).

    [11] [11] J. R. Mourant, I. J. Bigio, D. A. Jack, T. M. Johnson, H. D. Miller, "Measuring absorption coefficients in small volumes of highly scattering media: Sourcedetector separations for which path lengths do not depend on scattering properties," Appl. Opt. 36, 5655-5661 (1997).

    [12] [12] T. J. Dougherty, C. J. Gomer, B. W. Henderson, G. Jori, D. Kessel, M. Korbelik, J. Moan, Q. Peng, "Photodynamic therapy," J. Natl. Cancer Inst. 90, 889-905 (1998).

    [13] [13] H. U. Ahmed, D. Pendse, R. Illing, C. Allen, J. H. van der Meulen, M. Emberton, "Will focal therapy become a standard of care for men with localized prostate cancerff," Nat. Clin. Pract. Oncol. 4, 632-642 (2007).

    [14] [14] L. Ayaru, J. Wittmann, A. J. Macrobert, M. Novelli, S. G. Bown, S. P. Pereira, "Photodynamic therapy using verteporfin photosensitization in the pancreas and surrounding tissues in the Syrian golden hamster," Pancreatology 7, 20-27 (2007).

    [15] [15] H. R. Jager, M. N. Taylor, T. Theodossy, C. Hopper, "MR imaging-guided interstitial photodynamic laser therapy for advanced head and neck tumors," AJNR Am. J. Neuroradiol. 26, 1193-1200 (2005).

    [16] [16] S. P. Pereira, L. Ayaru, A. Rogowska, A. Mosse, A. R. Hatfield, S. G. Bown, "Photodynamic therapy of malignant biliary structures using meso-tetrahydroxyphenylchlorin," Eur. J. Gastroenterol. Hepatol. 19, 479-485 (2007).

    [17] [17] M. Zellweger, P. Grosjean, P. Monnier, H. van den Bergh, G. Wagnieres, "Stability of the fluorescence measurement of Foscan in the normal human oral cavity as an indicator of its content in early cancers of the esophagus and the bronchi," Photochem. Photobiol. 69, 605-610 (1999).

    [18] [18] D. Phillips, D. Dhami, R. Ostler, Z. Petrasek, "The dimerisation of phthalocyanines," Progress in Reaction Kinetics and Mechanism 28, 299-420 (2003).

    [19] [19] P. T. Chatlani, P. J. Nuutinen, N. Toda, H. Barr, A. J. Macrobert, J. Bedwell, S. G. Bown, "Selective necrosis in hamster pancreatic tumours using photodynamic therapy with phthalocyanine photosensitisation," Br. J. Surg. 79, 786-790 (1992).

    [20] [20] J. H. Woodhams, L. Kunz, S. G. Bown, A. J. Macrobert, "Correlation of real-time haemoglobin oxygen saturation monitoring during photodynamic therapy with microvascular effects and tissue necrosis in normal rat liver," Br. J. Cancer 91, 788-794 (2004).

    [21] [21] T. K. Lee, E. D. Baron, T. H. Foster, "Monitoring Pc 4 photodynamic therapy in clinical trials of cutaneous T-cell lymphoma using noninvasive spectroscopy," J. Biomed. Opt. 13, 030507 (2008).

    [22] [22] C. J. Tralau, H. Barr, D. R. Sandeman, T. Barton, M. R. Lewin, S. G. Bown, "Aluminum sulfonated phthalocyanine distribution in rodent tumors of the colon, brain and pancreas," Photochem. Photobiol. 46, 777-781 (1987).

    [23] [23] H. Barr, C. J. Tralau, A. J. Macrobert, N. Krasner, P. B. Boulos, C. G. Clark, S. G. Bown, "Photodynamic therapy in the normal rat colon with phthalocyanine sensitisation," Br. J. Cancer 56, 111-118 (1987).

    [24] [24] S. A. Prahl, "Hemoglobin spectra," Oregon Medical Laser Center, Oregon, USA (1999).

    [25] [25] A. J. Welch and M. J. van Gemert, Optical-Thermal Response of Laser-Irradiated Tissue, Plenum, 2005.

    [26] [26] S. Kascakova, B. Kruijt,H. S. de Bruijn, van der Ploegvan den Heuvel , D. J. Robinson, H. J. Sterenborg, A. Amelink, "Ex vivo quantification of mTHPC concentration in tissue: Influence of chemical extraction on the optical properties," J. Photochem. Photobiol. B 91, 99-107 (2008).

    [27] [27] K. Berg, J. C. Bommer, J. Moan, "Evaluation of sulfonated aluminum phthalocyanines for use in photochemotherapy. A study on the relative efficiencies of photoinactivation," Photochem. Photobiol. 49, 587- 594 (1989).

    [28] [28] R. Cubeddu, G. Canti, M. Musolino, A. Pifferi, P. Taroni, G. Valentini, "In vivo absorption spectrum of disulphonated aluminium phthalocyanine in a murine tumour model," J. Photochem. Photobiol. B 34, 229-235 (1996).

    [29] [29] L. Kunz, J. P. Connelly, J. H. Woodhams, A. J. Macrobert, "Photodynamic modification of disulfonated aluminium phthalocyanine fluorescence in a macrophage cell line," Photochem. Photobiol. Sci. 6, 940-948 (2007).

    [30] [30] P. Taroni, A. Pifferi, A. Torricelli, D. Comelli, R. Cubeddu, "In vivo absorption and scattering spectroscopy of biological tissues," Photochem. Photobiol. Sci. 2, 124-129 (2003).

    Tools

    Get Citation

    Copy Citation Text

    MARTIN R. AUSTWICK, JOSEPHINE H. WOODHAMS, VADZIM CHALAU, CHARLES A. MOSSE, CAROLINE ELIOT, LAURENCE LOVAT, ALEXANDER J. MACROBERT, IRVING J. BIGIO, STEPHEN G. BOWN. OPTICAL MEASUREMENT OF PHOTOSENSITIZER CONCENTRATION IN VIVO[J]. Journal of Innovative Optical Health Sciences, 2011, 4(2): 97

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: --

    Accepted: --

    Published Online: Jan. 10, 2019

    The Author Email: WOODHAMS JOSEPHINE H. (j.woodhams@ucl.ac.uk)

    DOI:10.1142/s1793545811001460

    Topics