[1] The metabolism of carcinoma cells. J. Cancer Res., 9, 148-163(1925).

[2] Otto Warburg’s contributions to current concepts of cancer metabolism. Nat. Rev. Cancer, 11, 325-337(2011).

[3] Lipid metabolism in cancer cells under metabolic stress. Br. J. Cancer, 120, 1090-1098(2019).

[4] Fundamentals of cancer metabolism. Sci. Adv., 2, e1600200(2016).

[5] De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. Br. J. Cancer, 100, 1369-1372(2009).

[6] The interplay between cell signalling and the mevalonate pathway in cancer. Nat. Rev. Cancer, 16, 718-731(2016).

[7] Triglycerides promote lipid homeostasis during hypoxic stress by balancing fatty acid saturation. Cell Rep., 24, 2596-2605.e5(2018).

[8] Greasing the wheels of the cancer machine: The role of lipid metabolism in cancer. Cell Metab., 31, 62-76(2020).

[9] Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation. Cell Rep., 9, 349-365(2014).

[10] Lipid metabolism and carcinogenesis, cancer development. Am. J. Cancer Res., 8, 778-791(2018).

[11] Lipid droplets and cellular lipid metabolism. Annu. Rev. Biochem., 81, 687-714(2012).

[12] Lipid metabolic reprogramming in cancer cells. Oncogenesis, 5, e189(2016).

[13] Emerging roles of lipid metabolism in cancer metastasis. Mol. Cancer, 16, 76(2017).

[14] 1H NMR visible lipids in the life and death of cells. Trends Biochem. Sci., 25, 357-362(2000).

[15] Mass spectrometry in the lipid study of cancer. Expert Rev. Proteomics, 18, 201-219(2021).

[16] Principles and methods of integrative genomic analyses in cancer. Nat. Rev. Cancer, 14, 299-313(2014).

[17] Mass spectrometry imaging to detect lipid biomarkers and disease signatures in cancer. Cancer Rep. (Hoboken), 2, e1229(2019).

[18] Multiplexed live-cell profiling with Raman probes. Nat. Commun., 12, 3405(2021).

[19] Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine. Science, 350, aaa8870(2015).

[20] Deciphering single cell metabolism by coherent Raman scattering microscopy. Curr. Opin. Chem. Biol., 33, 46-57(2016).

[21] Raman spectroscopy and imaging for cancer diagnosis. J. Healthc. Eng., 2018, 8619342(2018).

[22] Multiplex stimulated Raman scattering imaging cytometry reveals lipid-rich protrusions in cancer cells under stress condition. iScience, 23, 100953(2020).

[23] Raman imaging of small biomolecules. Annu. Rev. Biophys., 48, 347-369(2019).

[24] Imaging chemistry inside living cells by stimulated Raman scattering microscopy. Methods, 128, 119-128(2017).

[25] Advances in stimulated Raman scattering imaging for tissues and animals. Quant Imaging Med. Surg., 11, 1078-1101(2021).

[26] Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy. Science, 322, 1857-1861(2008).

[27] Spectrally modulated stimulated Raman scattering imaging with an angle-to-wavelength pulse shaper. Opt. Express, 21, 13864-13874(2013).

[28] Applications of coherent Raman scattering microscopies to clinical and biological studies. Analyst, 140, 3897-3909(2015).

[29] Assessing breast tumor margin by multispectral photoacoustic tomography. Biomed. Opt. Express, 6, 1273-1281(2015).

[30] Hyperspectral imaging with stimulated Raman scattering by chirped femtosecond lasers. J. Phys. Chem. B, 117, 4634-4640(2013).

[31] Coherent anti-stokes Raman scattering microscopy. Appl. Spectrosc., 61, 197-208(2007).

[32] Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Sci. Transl. Med., 5, 201ra119(2013).

[33] Applications of vibrational tags in biological imaging by Raman microscopy. Analyst, 142, 4018-4029(2017).

[34] Biological imaging of chemical bonds by stimulated Raman scattering microscopy. Nat. Methods, 16, 830-842(2019).

[35] Direct visualization of de novo lipogenesis in single living cells. Sci. Rep., 4, 6807(2014).

[36] Live-cell stimulated Raman scattering imaging of alkyne-tagged biomolecules. Angew. Chem. Int. Ed. Engl., 53, 5827-5831(2014).

[37] Noninvasive imaging of intracellular lipid metabolism in macrophages by Raman microscopy in combination with stable isotopic labeling. Anal. Chem., 84, 8549-8556(2012).

[38] Visualizing subcellular enrichment of glycogen in live cancer cells by stimulated Raman scattering. Anal. Chem., 92, 13182-13191(2020).

[39] D38-cholesterol as a Raman active probe for imaging intracellular cholesterol storage. J. Biomed. Opt., 21, 61003(2016).

[40] Live-cell imaging of alkyne-tagged small biomolecules by stimulated Raman scattering. Nat. Methods, 11, 410-412(2014).

[41] Quantitative chemical imaging with stimulated Raman scattering microscopy. Curr. Opin. Chem. Biol., 39, 24-31(2017).

[42] Reprogramming of fatty acid metabolism in cancer. Br. J. Cancer, 122, 4-22(2020).

[43] Lipid metabolism in cancer. FEBS J., 279, 2610-2623(2012).

[44] Cellular fatty acid metabolism and cancer. Cell Metab., 18, 153-161(2013).

[45] Cholesterol metabolism in cancer: Mechanisms and therapeutic opportunities. Nat. Metab., 2, 132-141(2020).

[46] Lipid droplets: Platforms with multiple functions in cancer hallmarks. Cell Death Dis., 11, 105(2020).

[47] Vibrational imaging of lipid droplets in live fibroblast cells with coherent anti-Stokes Raman scattering microscopy. J. Lipid Res., 44, 2202-2208(2003).

[48] Cholesterol sensing, trafficking, and esterification. Annu. Rev. Cell Dev. Biol., 22, 129-157(2006).

[49] The role of cholesterol in cancer. Cancer Res., 76, 2063-2070(2016).

[50] Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death. Nature, 567, 118-122(2019).

[51] In vitro exploration of ACAT contributions to lipid droplet formation during adipogenesis. J. Lipid Res., 59, 820-829(2018).

[52] Potentiating the antitumour response of CD8(+) T cells by modulating cholesterol metabolism. Nature, 531, 651-655(2016).

[53] Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer. Oncogene, 35, 6378-6388(2016).

[54] Acyl-coenzyme A: Cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines. Cancer Biol. Ther., 9, 1025-1032(2010).

[55] Avasimibe encapsulated in human serum albumin blocks cholesterol esterification for selective cancer treatment. ACS Nano, 9, 2420-2432(2015).

[56] Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1-mediated lipogenesis. Clin. Cancer Res., 22, 5337-5348(2016).

[57] Cholesterol esterification inhibition suppresses prostate cancer metastasis by impairing the Wnt/beta-catenin pathway. Mol. Cancer Res., 16, 974-985(2018).

[58] Cholesteryl ester accumulation induced by PTEN loss and PI3K/AKT activation underlies human prostate cancer aggressiveness. Cell Metab., 19, 393-406(2014).

[59] Multimodal metabolic imaging reveals pigment reduction and lipid accumulation in metastatic melanoma. BME Front., 2021, 1-17(2021).

[60] Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation. PLoS One, 13, e0193318(2018).

[61] Cholesterol esterification inhibition and imatinib treatment synergistically inhibit growth of BCR-ABL mutation-independent resistant chronic myelogenous leukemia. PLoS One, 12, e0179558(2017).

[62] Hyperspectral stimulated Raman scattering microscopy unravels aberrant accumulation of saturated fat in human liver cancer. Anal. Chem., 90, 6362-6366(2018).

[63] Lipid desaturation is a metabolic marker and therapeutic target of ovarian cancer stem cells. Cell Stem Cell, 20, 303-314.e5(2017).

[64] Three-dimensional chemical imaging of skin using stimulated Raman scattering microscopy. J. Biomed. Opt., 19, 111604(2014).

[65] Spectral tracing of deuterium for imaging glucose metabolism. Nat. Biomed. Eng., 3, 402-413(2019).

[66] Volumetric chemical imaging by clearing-enhanced stimulated Raman scattering microscopy. Proc. Natl. Acad. Sci. USA, 116, 6608-6617(2019).

[67] Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells. Nat. Commun., 11, 4830(2020).

[68] Optical imaging of metabolic dynamics in animals. Nat. Commun., 9, 2995(2018).

[69] Rafting down the metastatic cascade: The role of lipid rafts in cancer metastasis, cell death, and clinical outcomes. Cancer Res., 81, 5-17(2021).

[70] Lipid composition of the cancer cell membrane. J. Bioenerg. Biomembr., 52, 321-342(2020).

[71] Membrane cholesterol efflux drives tumor-associated macrophage reprogramming and tumor progression. Cell Metab., 29, 1376-1389.e4(2019).

[72] Label-free analysis of breast tissue polarity by Raman imaging of lipid phase. Biophys. J., 102, 1215-1223(2012).

[73] Coherent anti-Stokes Raman scattering imaging of lipids in cancer metastasis. BMC Cancer, 9, 42(2009).

[74] Metabolic activity induces membrane phase separation in endoplasmic reticulum. Proc. Natl. Acad. Sci. USA, 114, 13394-13399(2017).

[75] Dissecting lipid droplet biology with coherent Raman scattering microscopy. J. Cell Sci., 135, jcs252353(2022).

[76] Supermultiplexed vibrational imaging: From probe development to biomedical applications. Stimulated Raman Scattering Microscopy: Techniques and Applications,J.-X. Cheng,W. Min,Y. Ozeki,D. Polli., Chap. 21, 311-328(2022).

[77] [77] Jang H., Li Y., Fung A. A., Bagheri P., Hoang K., Skowronska-Krawczyk D., Chen X., Wu J. Y., Bintu B., Shi L., “Super-resolution stimulated Raman Scattering microscopy with A-PoD,” bioRxiv (2022), https://doi.org/10.1101/2022.06.04.494813.

[78] [78] Zhang W., Li Y., Fung A. A., Li Z., Jang H., Zha H., Chen X., Gao F., Wu J. Y., Sheng H., Yao J., Skowronska-Krawczyk D., Jain S., Shi L., “Multi-molecular hyperspectral PRM-SRS imaging,” bioRxiv (2022), https://doi.org/10.1101/2022.07.25.501472.

[79] Imaging sub-cellular methionine and insulin interplay in triple negative breast cancer lipid droplet metabolism. Front. Oncol., 12, 858017(2022).