The integral Windup phenomenon from a position angle control system in the aviation camera is more likely to happen when a big travel is given, which will affect the dynamic performance of the camera. To improve the dynamic response performance of the position-angle control system on this condition, this paper proposes a method based on the Anti-Windup variable structure adaptive PID control to design the position angle control system. A primary and secondary cascade dual loop was used to control the position of a position-angle mirror, and a variable structure adaptive PID control based on the Anti-Windup was adopted to control the compensation in the speed inner loop. The PID tuning method based on real-coded genetic algorithm was taken to tune the initial PID control parameters of speed inner loop, and the optimal index of parameter selection used punishment function to eliminate the overshoot. As mentioned above, the position- angle control system is able to achieve satisfactory performance in a large position given. Experiments show that the control strategy based on the Anti-Windup variable structure adaptive PID control avoids the position angle mirror coming into a saturation in the back stage after auto-focusing, increases the adjust time of back stage by 35.7% and improves the return performance of the position angle mirror.