Fig. 1. (a) The optical schematic of our customized dual-mode FFOCT system, (b) static FFOCT image acquired with a 4-phase modulation scheme, and (c) D-FFOCT image extracted through power spectral density analysis color-coding of temporal FFOCT interferograms. BS: beam splitter; LED: light emitting diode; MO: microscope objective; PZT: piezoelectric transducer. Scale bar: 50 µm.

Fig. 2. The depth-resolved static (upper) and dynamic (lower) FFOCT images of normal mouse retina acquired with the dual-mode FFOCT system covering the (a), (b) nerve fiber layer, (c), (d) ganglion cell layer, (e), (f) inner plexiform layer, inner nuclear layer [(g), (h) upper layer; (i), (j) lower layer], outer plexiform layer [upper right corner of (i), (j)], and (k), (l) outer nuclear layer. Scale bar: 50 µm.

Fig. 3. Dual-mode FFOCT images and the corresponding immunofluorescence images of the GCL acquired in early I/R injured mouse retinal tissue (upper) compared to normal mouse retinal tissue (lower). Scale bar: 50 µm.

Fig. 4. Dual-mode FFOCT image NFL in the nasal side and the vessels in the optic disk area. Scale bar: 50 µm.