Progress in Immunophotonics

[3] [3] T. Zal, G. Chodaczek. Intravital imaging of anti-tumor immune response and the tumor microenvironment［J］. Semin. Immunopathol., 2010, 32(3): 305～317

[4] [4] Z. Fan, J. A. Spencer, Y. Lu et al.. In vivo tracking of ′color-coded′ effector, natural and induced regulatory T cells in the allograft response［J］. Nature Med., 2010, 16(6): 718～722

[5] [5] R. N. Germain, M. J. Miller, M. L. Dustin et al.. Dynamic imaging of the immune system: progress, pitfalls and promise［J］. Nature Rev. Immunol., 2006, 6(7): 497～507

[6] [6] M. F. Krummel. Illuminating emergent activity in the immune system by real-time imaging［J］. Nature Immunol., 2010, 11(7): 554～557

[7] [7] W. Denk, J. H. Strickler, W. W. Webb. Two-photon laser scanning fluorescence microscopy［J］. Science, 1990, 248(4951): 73～76

[8] [8] R. Weissleder, M. J. Pittet. Imaging in the era of molecular oncology［J］. Nature, 2008, 452(7187): 580～589

[9] [9] B. A. Wilt, L. D. Burns, E. T. Wei Ho et al.. Advances in light microscopy for neuroscience［J］. Annu. Rev. Neurosci., 2009, 32: 435～506

[10] [10] M. J. Miller, S. H. Wei, I. Parker et al.. Two-photon imaging of lymphocyte motility and antigen response in intact lymph node［J］. Science, 2002, 296(5574): 1869～1873

[11] [11] M. D. Cahalan, I. Parker, S. H. Wei et al.. Two-photon tissue imaging: seeing the immune system in a fresh light［J］. Nature Rev. Immunol., 2002, 2(11): 872～880

[12] [12] F. Helmchen, W. Denk. Deep tissue two-photon microscopy［J］. Nature Methods, 2005, 2(12): 932～940

[13] [13] J. N. Kerr, W. Denk. Imaging in vivo: watching the brain in action［J］. Nature Rev. Neurosci., 2008, 9(3): 195～205

[14] [14] D. Li, X. Lü, S. Zeng et al.. Beam spot size evolution of Gaussian femtosecond pulses after angular dispersion［J］. Opt. Lett., 2008, 33(2): 128～130

[15] [15] S. Zeng, X. Lü, C. Zhan et al.. Simultaneous compensation for spatial and temporal dispersion of acousto-optical deflectors for two-dimensional scanning with a single prism［J］. Opt. Lett., 2006, 31(8): 1091～1093

[16] [16] L. V. Wang. Multiscale photoacoustic microscopy and computed tomography［J］. Nature Photon., 2009, 3(9): 503～509

[17] [17] X. Wang, Y. Pang, G. Ku et al.. Noninvasive laser-induced photoacoustic tomography for structural and functional in vivo imaging of the brain［J］. Nature Biotechnol., 2003, 21(7): 803～806

[18] [18] H. F. Zhang, K. Maslov, G. Stoica et al.. Functional photoacoustic microscopy for high-resolution and noninvasive in vivo imaging［J］. Nature Biotechnol., 2006, 24(7): 848～851

[19] [19] K. H. Song, E. W. Stein, J. A. Margenthaler et al.. Noninvasive photoacoustic identification of sentinel lymph nodes containing methylene blue in vivo in a rat model［J］. J. Biomed. Opt., 2008, 13(5): 054033

[20] [20] K. Maslov, H. F. Zhang, S. Hu et al.. Optical-resolution photoacoustic microscopy for in vivo imaging of single capillaries［J］. Opt. Lett., 2008, 33(9): 929～931

[21] [21] C. Zhang, K. Maslov, L. V. Wang. Subwavelength-resolution label-free photoacoustic microscopy of optical absorption in vivo［J］. Opt. Lett., 2010, 35(19): 3195～3197

[22] [22] S. Yang, D. Xing, Q. Zhou et al.. Functional imaging of cerebrovascular activities in small animals using high-resolution photoacoustic tomography［J］. Med. Phys., 2007, 34(8): 3294～3301

[23] [23] C. Kim, C. Favazza, L. V. Wang. In vivo photoacoustic tomography of chemicals: high-resolution functional and molecular optical imaging at new depths［J］. Chem. Rev., 2010, 110(5): 2756～2782

[24] [24] V. Ntziachristos, D. Razansky. Molecular imaging by means of multispectral optoacoustic tomography (MSOT)［J］. Chem. Rev., 2010, 110(5): 2783～2794

[25] [25] Chu Jun, Shi Hua, Yang Jie et al.. Optical visualization of molecular and cellular events: to decode 2008 Nobel Prize in chemistry［J］. Progress in Biochemistry and Biophysics, 2008, 35(10): 1104～1111

[26] [26] M. Pawlicki, H. A. Collins, R. G. Denning et al.. Two-photon absorption and the design of two-photon dyes［J］. Angew. Chem. Int. Ed. Engl., 2009, 48(18): 3244～3266

[27] [27] G. S. He, L. S. Tan, Q. Zheng et al.. Multiphoton absorbing materials: molecular designs, characterizations, and applications［J］. Chem. Rev., 2008, 108(4): 1245～1330

[28] [28] H. M. Kim, B. R. Cho. Two-photon probes for intracellular free metal ions, acidic vesicles, and lipid rafts in live tissues［J］. Acc. Chem. Res., 2009, 42(7): 863～872

[29] [29] M. Drobizhev, N. S. Makarov, S. E. Tillo et al.. Two-photon absorption properties of fluorescent proteins［J］. Nature Methods., 2011, 8(5): 393～399

[30] [30] D. Shcherbo, E. M. Merzlyak, T. V. Chepurnykh et al.. Bright far-red fluorescent protein for whole-body imaging［J］. Nature Methods, 2007, 4(9): 741～746

[31] [31] J. Chu, Z. Zhang, Y. Zheng et al.. A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions［J］. Biosens. Bioelectron., 2009, 25(1): 234～239

[32] [32] X. Shu, A. Royant, M. Z. Lin et al.. Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome［J］. Science, 2009, 324(5928): 804～807

[33] [33] M. Tomura, N. Yoshida, J. Tanaka et al.. Monitoring cellular movement in vivo with photoconvertible fluorescence protein “kaede” transgenic mice［J］. Proc. Natl. Acad. Sci. USA, 2008, 105(31): 10871～10876

[34] [34] G. D. Victora, T. A. Schwickert, D. R. Fooksman et al.. Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter［J］. Cell, 2010, 143(4): 592～605

[35] [35] K. A. Lukyanov, D. M. Chudakov, S. Lukyanov et al.. Innovation: photoactivatable fluorescent proteins［J］. Nature Rev. Mol. Cell. Biol., 2005, 6(11): 885～891

[36] [36] M. Fernandez-Suarez, A. Y. Ting. Fluorescent probes for super-resolution imaging in living cells［J］. Nature Rev. Mol. Cell. Biol., 2008, 9(12): 929～943

[37] [37] J. Lippincott-Schwartz, G. H. Patterson. Photoactivatable fluorescent proteins for diffraction-limited and super-resolution imaging［J］. Trends Cell. Biol., 2009, 19(11): 555～565

[38] [38] Yang Jie, Zhang Zhihong, Luo Qingming. Recent progress in fluorescent proteins research［J］. Acta Biophysica Sinica, 2010, 26(11): 1025～1035

[39] [39] Razansky Daniel, Distel Martin, Vinegoni Claudio et al.. Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo［J］. Nature Photon., 2009, 3(7): 412～417

[40] [40] H. Hutter. Five-colour in vivo imaging of neurons in caenorhabditis elegans［J］. J. Microsc., 2004, 215(Pt 2): 213～218

[41] [41] T. Kogure, S. Karasawa, T. Araki et al.. A fluorescent variant of a protein from the stony coral montipora facilitates dual-color single-laser fluorescence cross-correlation spectroscopy［J］. Nature Biotechnol., 2006, 24(5): 577～581

[42] [42] J. Livet, T. A. Weissman, H. Kang et al.. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system［J］. Nature, 2007, 450(7166): 56～62

[43] [43] C. Wu, J. Zheng, C. Huang et al.. Hybrid silica-nanocrystal-organic dye superstructures as post-encoding fluorescent probes［J］. Angew. Chem. Int. Ed. Engl., 2007, 46(28): 5393～5396

[44] [44] B. H. Zinselmeyer, J. N. Lynch, X. Zhang et al.. Video-rate two-photon imaging of mouse footpad: a promising model for studying leukocyte recruitment dynamics during inflammation［J］. Inflamm. Res., 2008, 57(3): 93～96

[45] [45] T. Chtanova, M. Schaeffer, S. J. Han et al.. Dynamics of neutrophil migration in lymph nodes during infection［J］. Immunity, 2008, 29(3): 487～496

[46] [46] N. C. Peters, J. G. Egen, N. Secundino et al.. In vivo imaging reveals an essential role for neutrophils in leishmaniasis transmitted by sand flies［J］. Science, 2008, 321(5891): 970～974

[47] [47] B. McDonald, K. Pittman, G. B. Menezes et al.. Intravascular danger signals guide neutrophils to sites of sterile inflammation［J］. Science, 2010, 330(6002): 362～366

[48] [48] J. C. Waite, I. Leiner, P. Lauer et al.. Dynamic imaging of the effector immune response to listeria infection in vivo［J］. PLoS Pathog., 2011, 7(3): e1001326

[49] [49] J. Larmann, T. Frenzel, A. Hahnenkamp et al.. In vivo fluorescence-mediated tomography for quantification of urokinase receptor-dependent leukocyte trafficking in inflammation［J］. Anesthesiology, 2010, 113(3): 610～618

[50] [50] B. Breart, F. Lemaitre, S. Celli et al.. Two-photon imaging of intratumoral cd8(+) T cell cytotoxic activity during adoptive t cell therapy in mice［J］. J. Clinical Investigation, 2008, 118(4): 1390～1397

[51] [51] A. Boissonnas, L. Fetler, I. S. Zeelenberg et al.. In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor［J］. J. Experimental Medicine, 2007, 204(2): 345～356

[52] [52] P. Mrass, H. Takano, L. G. Ng et al.. Random migration precedes stable target cell interactions of tumor-infiltrating T cells［J］. J. Experimental Medicine, 2006, 203(12): 2749～2761

[53] [53] J. Deguine, B. Breart, F. Lemaitre et al.. Intravital imaging reveals distinct dynamics for natural killer and cd8(+) T cells during tumor regression［J］. Immunity, 2010, 33(4): 632～644

[54] [54] J. B. Wyckoff, Y. Wang, E. Y. Lin et al.. Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors［J］. Cancer Res., 2007, 67(6): 2649～2656

[55] [55] M. J. Pittet. Behavior of immune players in the tumor microenvironment［J］. Curr. Opin. Oncol., 2009, 21(1): 53～59

[56] [56] S. Celli, M. L. Albert, P. Bousso. Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy［J］. Nature Med., 2011, 17(6): 744～749

[57] [57] Z. Fan, J. A. Spencer, Y. Lu et al.. In vivo tracking of “color-coded” effector, natural and induced regulatory T cells in the allograft response［J］. Nature Med., 2010, 16(6): 718～722

[58] [58] D. Kreisel, R. G. Nava, W. Li et al.. In vivo two-photon imaging reveals monocyte-dependent neutrophil extravasation during pulmonary inflammation［J］. Proc. Natl. Acad. Sci. USA, 2010, 107(42): 18073～18078

[59] [59] X. Li, G. L. Ferrel, M. C. Guerra et al.. Preliminary safety and efficacy results of laser immunotherapy for the treatment of metastatic breast cancer patients［J］. Photochem. Photobiol. Sci., 2011, 10(5): 817～821

[60] [60] X. Li, M. F. Naylor, H. Le et al.. Clinical effects of in situ photoimmunotherapy on late-stage melanoma patients: a preliminary study［J］. Cancer Biol. Ther., 2010, 10(11): 1081～1087