Study on Cefradine Granules Component Analysis and Calibration Transfer Method Based on Near-Infrared Spectroscopy

Zi-kun ZHOU; Chen-xi LI; Zhe WANG; Rong LIU; Wen-liang CHEN; Ke-xin XU

doi:10.3964/j.issn.1000-0593(2020)11-3562-05

Spectroscopy and Spectral Analysis, Volume. 40, Issue 11, 3562(2020)

Study on Cefradine Granules Component Analysis and Calibration Transfer Method Based on Near-Infrared Spectroscopy

Zi-kun ZHOU^1,1、*, Chen-xi LI^1,1, Zhe WANG^1,1, Rong LIU^1,1, Wen-liang CHEN^1,1, and Ke-xin XU^1,1

Author Affiliations

¹[in Chinese]

¹1. State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China

show less

Abstract Get PDF(in Chinese)

Figures & Tables(5)

Fig. 1. Relation between evolution step and mean square error

Download full size

View in Article

Fig. 2. The relation between the normalized parameters (RMSEP and PR) and the number of conversion sets
(a): Cefradine; (b): Cephalexin; (c): Moisture content

Download full size

View in Article

Table 1. Modeling parameters and prediction results of two spectrometers

View table

View in Article

Table 1. Modeling parameters and prediction results of two spectrometers

成分	头孢拉定		头孢氨苄		水分
仪器	Frontier	Antaris	Frontier	Antaris	Frontier	Antaris
RMSEC/(mg·g^-1)	1.83	2.09	0.089	0.188	0.121	0.147
RMSEP/(mg·g^-1)	2.92	3.63	0.304	0.316	0.147	0.189
R²	0.988	0.982	0.623	0.611	0.874	0.767

Table 2. Calibration transfer parameters and spectral differences

View table

View in Article

Table 2. Calibration transfer parameters and spectral differences

成分	头孢拉定	头孢氨苄	水分
窗口宽度	9	11	9
传递后ARMS	0.075	0.076	0.083
Pr/%	91.1	94.7	94.2
主仪器RMSEP/(mg·g^-1)	2.264	0.210	0.131
从仪器传递前RMSEP/(mg·g^-1)	8.82	0.481	0.362
从仪器传递后RMSEP/(mg·g^-1)	3.50	0.314	0.172
从仪器传递前RPE/%	9.67	52.14	19.25
从仪器传递后RPE/%	4.37	31.12	11.67

Table 3. Calibration transfer and evaluation parameters of two algorithms
View table
View in Article
Table 3. Calibration transfer and evaluation parameters of two algorithms
成分头孢拉定头孢氨苄水分
方法 MC K-S MC K-S MC K-S
ARMS_un 0.251 0.244 0.332 0.317 0.345 0.328
ARMS 0.075 0.081 0.076 0.083 0.083 0.091
Pr/% 91.1 89.0 94.7 93.1 94.2 92.3
RMSEP/(mg·g^-1) 3.50 3.59 0.314 0.288 0.172 0.179

Tools

Get Citation

Copy Citation Text

Zi-kun ZHOU, Chen-xi LI, Zhe WANG, Rong LIU, Wen-liang CHEN, Ke-xin XU. Study on Cefradine Granules Component Analysis and Calibration Transfer Method Based on Near-Infrared Spectroscopy[J]. Spectroscopy and Spectral Analysis, 2020, 40(11): 3562

Download Citation

EndNote(RIS)BibTex Plain Text

Set citation alerts for article

Save article for my favorites