Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images

Qianfeng ZHAO; Xin MING; Bo LIU; Chunhui TANG

doi:10.11889/j.1000-3436.2022-0090

Journal of Radiation Research and Radiation Processing, Volume. 41, Issue 1, 010303(2023)

Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images

Qianfeng ZHAO1...2, Xin MING3, Bo LIU4, and Chunhui TANG12,* |Show fewer author(s)

¹Department of Oncology, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441021, China

²Institute of Oncology, Hubei University of Arts and Science, Xiangyang 441021, China

³School of Biomedical Engineering, Tianjin Medical University, Tianjin 300050, China

⁴Shandong Cancer Hospital, Jinan 250117, China

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Figures & Tables(6)

Fig. 1. Calibrated CT value-relative electron density curves

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Fig. 2. Example of isodose curves distribution and DVH plot results: (a) isodose distribution for pCT planning; (b) isodose distribution for iCBCT planning; (c) comparison of DVH diagrams of the two plans (color online)

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Fig. 3. Comparison of differences in CT values between iCBCT and pCT images: (a) pCT images; (b) iCBCT images; (c) profiles on the orange line in (a) and (b), display window [1 000, 200] (color online)

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Table 1. Dose volume limits of organ at risk (OAR)

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Table 1. Dose volume limits of organ at risk (OAR)

危及器官 Organ at risk	剂量体积限值 Dose volume limits
膀胱 Bladder	V₅₀<50%
直肠 Rectum	V₅₀<40%，V₄₀<50%
股骨头 Femoral head	V₄₀<5%，D_max<52 Gy
小肠 Small intestine	V₅₀<10%，D_mean<30 Gy
卵巢 Ovary	D_max<12 Gy
睾丸 Testis	D_max<4 Gy

Table 2. Results of target dosimetric parameters

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Table 2. Results of target dosimetric parameters

参数Parameter	D₂ / cGy	D₉₈ / cGy	D_mean / cGy	CI	HI
pCT	6 255±84	5 895±57	6 116±74	0.877±0.034	0.059±0.016
CBCT	6 287±71	5 875±53	6 074±95	0.860±0.035	0.068±0.017
t	-1.599	1.346	1.918	-2.065	1.837
p	>0.05	>0.05	>0.05	>0.05	>0.05

Table 3. Results of OARs dosimetric parameters

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Table 3. Results of OARs dosimetric parameters

参数Parameter		D_mean / cGy	D₅ / cGy	V₂₀ / %	V₃₀ / %	V₄₀ / %
左股骨头 Left femoral head	pCT	2 222±166	3 177±285	74.66±6.26	18.76±7.22	1.65±0.82
	CBCT	2 224±169	3 163±285	73.96±6.34	19.04±7.35	1.63±0.81
	t	-0.053	0.195	0.428	-0.151	0.095
	p	>0.05	>0.05	>0.05	>0.05	>0.05
右股骨头 Right femoral head	pCT	2 125±246	3 005±468	75.28±8.99	15.25±8.50	1.94±0.92
	CBCT	2 122±247	2 997±467	74.69±8.94	15.16±8.49	1.95±0.93
	t	0.035	0.069	0.253	0.042	-0.073
	p	>0.05	>0.05	>0.05	>0.05	>0.05
直肠 Rectum	pCT	2 725±428	4 305±543	59.19±11.33	38.60±10.97	21.02±10.06
	CBCT	2 762±428	4 458±558	60.09±11.66	39.23±11.16	21.14±10.29
	t	-0.339	-0.368	-0.301	-0.223	-0.042
	p	>0.05	>0.05	>0.05	>0.05	>0.05
膀胱 Bladder	pCT	3 772±167	4 589±573	97.23±2.31	73.81±5.88	45.01±7.54
	CBCT	3 834±173	4 619±570	96.16±2.47	75.09±5.94	45.72±7.69
	t	-1.422	-0.209	1.752	-0.840	-0.367
	p	>0.05	>0.05	>0.05	>0.05	>0.05

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Qianfeng ZHAO, Xin MING, Bo LIU, Chunhui TANG. Study on dose calculation of pelvic tumor radiotherapy planning based on iCBCT images[J]. Journal of Radiation Research and Radiation Processing, 2023, 41(1): 010303

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