Chinese Optics Letters, Volume. 18, Issue 12, 121705(2020)

Deep learning virtual colorful lens-free on-chip microscopy

Hua Shen1,2,3、* and Jinming Gao1,2
Author Affiliations
  • 1School of Electronic Engineering and Optoelectronic Technology, Nanjing University of Science and Technology, Nanjing 210094, China
  • 2MIIT Key Laboratory of Advanced Solid Laser, Nanjing University of Science and Technology, Nanjing 210094, China
  • 3Department of Material Science and Engineering, University of California Los Angeles, Los Angeles, CA 90095, USA
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    Figures & Tables(5)
    Lens-free on-chip microscope setup. (a) Schematic of lens-free on-chip microscopy. (b) Experimental lens-free on-chip microscope setup. (c) An example image of H&E stained pathological tumor tissue.
    Computational algorithm flowchart to get a virtually colorized lens-free on-chip microscopy image.
    Deep learning GAN established to achieve virtual colorization.
    Data processing to achieve virtual colorful lens-free on-chip microscopy. The yellow scale bar is 200 μm.
    Comparisons of lens-free on-chip microscopy image, bench-top commercial microscopy image, and virtual colorization image, which are image pairs of ROIs #1, #2, and #3 in Fig. 4.
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    Hua Shen, Jinming Gao, "Deep learning virtual colorful lens-free on-chip microscopy," Chin.Opt.Lett. 18, 121705 (2020)

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    Paper Information

    Category: Biophotonics

    Received: Aug. 22, 2020

    Accepted: Oct. 29, 2020

    Posted: Oct. 29, 2020

    Published Online: Dec. 8, 2020

    The Author Email: Hua Shen (edward_bayun@163.com)

    DOI:10.3788/COL202018.121705

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