Laser & Optoelectronics Progress, Volume. 58, Issue 18, 1811006(2021)

Application of Deep Learning in Digital Holographic Microscopy

Zhang Meng1, Hao Ding1, Shouping Nie1, Jun Ma2, and Caojin Yuan1、*
Author Affiliations
  • 1Jiangsu Key Laboratory for Opto-Electronic Technology, School of Physics and Technology, Nanjing Normal University, Nanjing, Jiangsu 210023, China
  • 2School of Electronic Engineering and Optoelectronic Techniques, Nanjing University of Science and Technology, Nanjing, Jiangsu 210094, China
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    Figures & Tables(13)
    Schematic diagram of digital holographic recording
    Schematic of deep neural network
    Network architecture. (a) Convolutional neural network; (b) U-net[38]
    Relationship between error between output and label in training set, test set, and validation set and number of iterations. (a) Training set and test set; (b) validation set
    Deep-learning-based hologram reconstruction. (a) Phase reconstruction of diffraction intensity map based on end-to-end deep learning[53]; (b) removal of twin images in in-line holographic reconstruction based on deep learning[28]; (c) deep-learning-based autofocusing and removal of twin-images with extended depth-of-field[54]; (d) autofocus and extended depth of field in in-line holographic reconstruction based on deep learning[31]; (e) amplitude and phase reconstruction of off-axis hologram based on deep learning[55]
    Deep-learning-based hologram reconstruction with unpaired data[57]. (a) Process of network training (Xi∈X: hologram; Yi∈Y: phase image; G & F: generator; DY: determine the authenticity of the images generated by G; DX: determine the authenticity of the images generated by F; Lcyc(D,F): loss of cyclic consistency; LY(G,DY,X,Y): antagonistic loss between DY and G; LX(F,DX,Y,X): antagonistic loss between DX and F); (b) reconstruction results (I: untrained hologram of input network for testing; II, III: reconstruction based on traditional methods and deep learning; IV: real phase distribution)
    Deep-learning-based autofocusing and phase reconstruction. (a) Phase recovery of defocus hologram based on deep learning[26]; (b) holographic self-focusing reconstruction based on end-to-end deep learning[66]
    Deep-learning-based holographic reconstruction noise suppression. (a) Coherent noise suppression without clean data based on deep learning[77]; (b) speckle noise suppression of in-line holographic reconstructed image based on deep learning[25]; (c) off-axis hologram speckle noise suppression based on deep learning[81]
    Resolution enhancement of hologram reconstruction based on deep learning[82]
    Deep-learning-based noise-free quantitative phase imaging of in-line holography[26]. (a) Method to achieve the noise-free quantitative phase image; (b) training dataset generation and network training process
    Deep-learning-based hologram generation[89]
    Deep-learning-based cross-modality image transformations[91]
    High-resolution numerical dark-field microscopy imaging based on deep learning[98]
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    Zhang Meng, Hao Ding, Shouping Nie, Jun Ma, Caojin Yuan. Application of Deep Learning in Digital Holographic Microscopy[J]. Laser & Optoelectronics Progress, 2021, 58(18): 1811006

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    Paper Information

    Category: Imaging Systems

    Received: Jun. 2, 2021

    Accepted: Jul. 20, 2021

    Published Online: Sep. 3, 2021

    The Author Email: Yuan Caojin (yuancj@njnu.edu.cn)

    DOI:10.3788/LOP202158.1811006

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