In the context of deep-space exploration， such as the Tianwen-1 mission， reliability over a long working time is an essential requirement for the main control unit of the high-resolution camera. To improve the anti-single event effect and reliability of the master FPGA， an anti-fuse FPGA is used for the software system design. Functions such as focusing unit control， time code punctuality， and time correction， managed by the master FPGA， are safety-critical items. To improve the robustness of the software， the main control FPGA design employs a two-division control method based on the acceleration and deceleration curve for the optical-mechanical structure of the focusing mechanism. A stepper motor driver is used to match the focusing speed and avoid the resonance frequency of the mechanism， for the focusing mechanism to run smoothly； at the same time， when the Tianwen-1 surround is in the ring fire section， the high-resolution camera needs to perform shooting tasks by following delayed commands， creating a requirement for highly accurate timing. Thus， the master control FPGA design must ensure time code punctuality and timing function such that the high-resolution camera accurately executes the shooting task. The experimental results show that the movement time of the focusing mechanism is 112.2 ms and the accuracy of time keeping is 1.25 s. The design satisfies the requirements of a stable operation of the focusing unit and reliable timing.