This study investigated the preparation of high-strength Al-Mg-Sc-Zr alloy samples by laser melting deposition technology. The effects of energy density and powder feeding rate modifications on the density, microstructural evolution, and mechanical properties of the deposited samples were investigated using metallographic, scanning electron microscopes, microhardness, and tensile properties at room temperature. Results showed that under a constant powder feeding rate, the deposited samples' densification behavior and density gradually increased with an increase in energy density. This trend became more significant with an increase in the powder feeding rate. Hence, when the powder feeding rate was set to 5.5 g/min, the density of 50-150 J/mm² samples specifically increased from 97.88% to 99.47%. Nevertheless, the sample with the best comprehensive mechanical properties was deposited under optimized technological conditions, namely an energy density of 100 J/mm² and a powder feeding rate of 2.5 g/min. Its density, yield strength, tensile strength, elongation, and microhardness were 99.51%, 268 MPa, 450 MPa, 18.4%, and 120.18 HV_0.2, respectively.