Chinese Journal of Quantum Electronics, Volume. 32, Issue 1, 1(2015)

Discriminant analysis for levocetirizine hydrochloride tablets based on near-infrared diffusion spectroscopy

Fenfen CHEN*... Minguang GAO and Liang XU |Show fewer author(s)
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    As there are many different kinds of medicine on the market, it’s significant to regulate medical market and ensure people’s medication safety by identification analysis of different brands of drug. Spectral library discriminant analysis was applied to establish the qualitative identification model for different brands of levocetirizine hydrochloride tablets based on near-infrared diffusion spectroscopy. The spectral pretreatment method used consisted of vector normalization method and derivative method. Then the validation set was used to test the model. The results showed that the model can’t correctly identify two samples of the same manufacturer, but samples from different manufacturers were classified correctly by the discriminant model, and the accuracy was 100%. This method can be used for rapid identification of similar medicines from different manufactures.

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    CHEN Fenfen, GAO Minguang, XU Liang. Discriminant analysis for levocetirizine hydrochloride tablets based on near-infrared diffusion spectroscopy[J]. Chinese Journal of Quantum Electronics, 2015, 32(1): 1

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    Paper Information

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    Received: Mar. 5, 2014

    Accepted: --

    Published Online: Jan. 27, 2015

    The Author Email: Fenfen CHEN (ffchen@aiofm.ac.cn)

    DOI:10.3969/j.issn.1007-5461. 2015.01.001

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