Journal of Innovative Optical Health Sciences, Volume. 10, Issue 6, 1742002(2017)

Fiber-integrated Brillouin microspectroscopy: Towards Brillouin endoscopy

Irina V. Kabakova**... YuChen Xiang, Carl Paterson and Peter Torok |Show fewer author(s)
Author Affiliations
  • Blackett Laboratory, Imperial College London, Prince Consort Road SW7 2AZ, London, UK
  • show less

    Brillouin imaging (BI) for micromechanical characterization of tissues and biomaterials is a fast-developing field of research with a strong potential for medical diagnosis of disease-modified tissues and cells. Although the principles of BI imply its compatibility with in vivo and in situ measurements, the integration of BI with a flexible catheter, capable of reaching the region of interest within the body, is yet to be reported. Here, for the first time, we experimentally investigate integration of the Brillouin spectroscope with standard optical fiber components to achieve a Brillouin endoscope. The performance of single-fiber and dual-fiber endoscopes are demonstrated and analyzed. We show that a major challenge in construction of Brillouin endoscopes is the strong backward Brillouin scattering in the optical fiber and we present a dual-fiber geometry as a possible solution. Measurements of Brillouin spectra in test liquids (water, ethanol and glycerol) are demonstrated using the dual-fiber endoscope and its performance is analyzed numerically with the help of a beam propagation model.

    Tools

    Get Citation

    Copy Citation Text

    Irina V. Kabakova*, YuChen Xiang, Carl Paterson, Peter Torok. Fiber-integrated Brillouin microspectroscopy: Towards Brillouin endoscopy[J]. Journal of Innovative Optical Health Sciences, 2017, 10(6): 1742002

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: Jul. 30, 2017

    Accepted: Aug. 18, 2017

    Published Online: Jan. 10, 2019

    The Author Email: Kabakova* Irina V. (i.kabakova@imperial.ac.uk)

    DOI:10.1142/s1793545817420020

    Topics