EDTA-LDH/zeolite composite material was synthesized in two steps by hydrothermal and reconstruction method and used for the removal of Cd2+, Pb2+, and Cu2+ from aqueous solution. The adsorption effect and mechanism of EDTA-LDH/zeolite on Cd2+, Pb2+ and Cu2+ in single and mixed heavy metal ion solutions under different conditions were systematically investigated. The results show that the best adsorption performance of EDTA-LDH/zeolite is achieved when the dosage of EDTA-LDH/zeolite is 0.05 g, the concentration of heavy metal ions is 1 500 mg/L, the pH value is 6.5, and the adsorption time is 24 h. Competing adsorption between heavy metal ions, the maximum adsorption capacities of EDTA-LDH/zeolite for Cd2+, Pb2+, and Cu2+ are 65.33, 98.35, and 108.51 mg/g, respectively. During the removal process, various mechanisms such as precipitation, surface complexation, and chelation work synergistically. The removal behavior of EDTA-LDH/zeolite are all consistent with Langmuir isotherm model and pseudo second-order kinetic model.