In this study, impact toughness samples of GH4169 are prepared by selective laser melting (SLM), and the microstructures of these samples are observed. The results show that in the preferred range of the SLM process parameters, the samples form a uniform orientation of the solidified columnar grain refinement arrangement. For a power of P=260 W and scanning speed of ν=0.9 m/s, the impact toughness of the GH4169 samples at room temperature is 43.9 J/cm ², and with the increase of laser power and scanning speed, the impact toughness continuously decreases, and the fracture of the impact sample has obvious transgranular characteristics.