Journal of Innovative Optical Health Sciences, Volume. 9, Issue 4, 1630006(2016)
Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy
Upconversion nanoparticles (UCNPs) as a promising material are widely studied due to their unique optical properties. The material can be excited by long wavelength light and emit visible wavelength light through multiphoton absorption. This property makes the particles highly attractive candidates for bioimaging and therapy application. This review aims at summarizing the synthesis and modification of UCNPs, especially the applications of UCNPs as a theranostic agent for tumor imaging and therapy. The biocompatibility and toxicity of UCNPs are also further discussed. Finally, we discuss the challenges and opportunities in the development of UCNP-based nanoplatforms for tumor imaging and therapy.
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Wenkai Fang, Yanchun Wei. Upconversion nanoparticle as a theranostic agent for tumor imaging and therapy[J]. Journal of Innovative Optical Health Sciences, 2016, 9(4): 1630006
Received: Nov. 14, 2015
Accepted: Mar. 2, 2016
Published Online: Dec. 27, 2018
The Author Email: Fang Wenkai (fwkoneway@163.com)