The dome seeing is an important influencing factor for imaging quality of ground-based large-aperture telescopes. Seeing is mainly due to the uneven change in the refractive index of air. First， theoretical analysis shows that the main factors affecting the refractive index of air are the temperature， velocity， and pressure of the air. Then， with the help of CFD fluid simulation software， the temperature field， velocity field， and pressure field changes of the air near the telescope dome are obtained， and the change of the refractive index of the air around the dome and telescope is calculated. Thus， the effect of dome seeing produced by domes of different structural forms on telescopic imaging can be evaluated. The simulation analysis shows that the lifting dome is more conducive to the rapid change and stability of the temperature， speed， and pressure of the air around the telescope to reduce the impact of dome seeing. From the perspective of dome seeing， this paper provides a guide for the scheme selection and design of a dome at the 4-meter level and larger telescopes.