Laser & Optoelectronics Progress, Volume. 57, Issue 15, 153006(2020)

Near-Infrared Spectroscopy Characteristics of Glucose in Tissue Phantom

Shan Huang, Shuyuan Zhu, Mengmeng Zhao, and Jihong Feng*
Author Affiliations
  • Intelligent Physiological Measurement and Clinical Translation, Beijing International Base for Scientific and Technological Cooperation, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China
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    Diabetes is increasingly threatening human health. However, noninvasive blood glucose detection methods for clinical use have not yet been developed. To solve this crucial problem, we study the spectral characteristics of light source through different mass concentrations of glucose in a solution. The wavelength range is 600-1300 nm, and the absorption spectral characteristics of glucose solutions with different mass concentrations and the reflection spectral characteristics of 2% Intralipid tissue phantoms with different glucose mass concentrations are studied. The spectral characteristics are evaluated based on their monotonicity, linearity and sensitivity. Experimental results show that light waves are absorbed in the range of 1140-1210 and 1130-1200 nm and those reflected in the range of 1010-1130 and 1150-1300 nm exhibited monotonicity, excellent linearity, and high sensitivity. Thus, light waves with these characteristics are expected to realize noninvasive blood glucose detection and also to improve accuracy and sensitivity, thereby promoting the application of optical noninvasive methods in clinical blood glucose detection.

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    Shan Huang, Shuyuan Zhu, Mengmeng Zhao, Jihong Feng. Near-Infrared Spectroscopy Characteristics of Glucose in Tissue Phantom[J]. Laser & Optoelectronics Progress, 2020, 57(15): 153006

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    Paper Information

    Category: Spectroscopy

    Received: Mar. 1, 2020

    Accepted: Mar. 25, 2020

    Published Online: Aug. 4, 2020

    The Author Email: Feng Jihong (jhfeng@bjut.edu.cn)

    DOI:10.3788/LOP57.153006

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