Laser & Optoelectronics Progress, Volume. 52, Issue 8, 81704(2015)
A Comparative Study and Evaluation on Several Typical Iterative Methods for Bioluminescence Tomography
Bioluminescence tomography (BLT) has recently emerged as a promising preclinical imaging modality.Iterative methods based on sparse regularization play a critical role in solving the ill-posed BLT inverse problem.Four kinds of typical iterative methods based on l1 regularization were briefly introduced and applied to reconstruct the bioluminescent source location and intensity,which include interior-point methods,homotopy methods,firstorder methods,and augmented Lagrangian methods.Numerical experiments on a digital inhomogeneous mouse model and in vivo experiments were conducted to evaluate the performance of these methods in terms of localization accuracy,reconstructed intensity and power.
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Liu Hejuan, Hou Yuqing, He Xiaowei, Pu Xin. A Comparative Study and Evaluation on Several Typical Iterative Methods for Bioluminescence Tomography[J]. Laser & Optoelectronics Progress, 2015, 52(8): 81704
Category: Medical Optics and Biotechnology
Received: Feb. 17, 2015
Accepted: --
Published Online: Jul. 29, 2015
The Author Email: Hejuan Liu (liuhejuan012@126.com)