Based on the ideal coordinate surface, a model of large aperture membrane diffractive lens and wavefront aberration was established. Firstly, the model of segmented lens deformation error was built. Secondly, according to the wavefront aberration relationship between segmented lens and large aperture membrane diffractive lens, the deformation error accuracy limitations of the large aperture membrane diffractive lens by segmented lens of different regions was investigated. The edge wrinkle sag and sphere sag were demonstrated. At last, taking wavefront aberration of all segmented lens to fit the Zernike polynomial, the lower order aberration were obtained. This work can provide references for correcting image system aberration and assembling large aperture membrane diffractive lens on engineering.