Journal of Inorganic Materials, Volume. 35, Issue 8, 867(2020)

Research Progress on Functional Modifications and Applications of Bioceramic Scaffolds

Shaojie DONG1...2, Xudong WANG2, Steve Guofang SHEN2,3, Xiaohong WANG1,* and Kaili LIN2,* |Show fewer author(s)
Author Affiliations
  • 1Shanghai Engineering Research Center of Tooth Restoration and Regeneration, School & Hospital of Stomatology, Tongji University, Shanghai 200072, China
  • 2Shanghai Ninth People’s Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • 3Shanghai University of Medicine & Health Sciences, Shanghai 201318, China;
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    Porous bioceramic scaffolds, which possess attractive biocompatibility, ability to guide tissue regeneration and porous surface morphologies and channels beneficial to ingrowth of new born tissues, have seized increasing attentions and been widely applied in the field of hard tissue restoration. Whereas, the weak osteoinductive activity, monotonous biological function and poor mechanical property have restrained the therapeutic efficacy and wider application of bioceramic scaffolds. In view of this, we intended to introduce the existing modification methods of bioceramic scaffolds, including the surface modification with functional coating, construction of surface micro-/nano- structures, functional element doping and enhancement of mechanical property, along with the state of the research progresses in the improvement of biocompatibility, bone defect restoration, drug delivery, tumor therapy, and antibacterial capacity of multifunctional bioceramic scaffolds. In addition, potential research directions and applications of functionally modified bioceramic scaffolds are prospected to provide references for the related exploration afterwards.

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    Shaojie DONG, Xudong WANG, Steve Guofang SHEN, Xiaohong WANG, Kaili LIN. Research Progress on Functional Modifications and Applications of Bioceramic Scaffolds[J]. Journal of Inorganic Materials, 2020, 35(8): 867

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    Paper Information

    Category: REVIEW

    Received: Nov. 4, 2019

    Accepted: --

    Published Online: Mar. 15, 2021

    The Author Email: WANG Xiaohong (xiaohongwang@tongji.edu.cn), LIN Kaili (lklecnu@aliyun.com)

    DOI:10.15541/jim20190561

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