Chinese Journal of Lasers, Volume. 47, Issue 2, 207035(2020)
Photoacoustic Microscopy Based on Highly Sensitive Ultrasound Transducer
In photoacoustic microscopy (PAM), detection sensitivity is an important factor for determining imaging quality and depth, which can affect photoacoustic imaging applications in biomedical engineering. To improve the detection sensitivity and signal-to-noise ratio (SNR), a miniature amplifier was integrated close to an ultrasound transducer for front-end signal amplification and output impedance matching. An optical resolution PAM was developed based on the fabricated prototype transducer to perform 3D imaging of phantoms and small vessels of the mouse ear. Experimental results show that the SNR is improved by over 10 dB. The proposed PAM has the potential to be used for monitoring and quantitatively analyzing weak physiological changes.
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Yang Chen, Jiao Yang, Zhu Xinle, Jian Xiaohua, George Sergiadis, Cui Yaoyao. Photoacoustic Microscopy Based on Highly Sensitive Ultrasound Transducer[J]. Chinese Journal of Lasers, 2020, 47(2): 207035
Category: biomedical photonics and laser medicine
Received: Sep. 6, 2019
Accepted: --
Published Online: Feb. 21, 2020
The Author Email: Yaoyao Cui (cuiyy@sibet.ac.cn)