Chinese Physics B, Volume. 29, Issue 8, (2020)
Detection of HIV-1 antigen based on magnetic tunnel junction sensors
We report a p24 (HIV disease biomarker) detection assay using an MgO-based magnetic tunnel junction (MTJ) sensor and 20-nm magnetic nanoparticles. The MTJ array sensor with sensing area of 890 × 890 μm2 possessing a sensitivity of 1.39 %/Oe was used to detect p24 antigens. It is demonstrated that the p24 antigens could be detected at a concentration of 0.01 μg/ml. The development of bio-detection systems based on magnetic tunnel junction sensors with high-sensitivity will greatly benefit the early diagnosis of HIV.
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Li Li, Kai-Yu Mak, Yan Zhou. Detection of HIV-1 antigen based on magnetic tunnel junction sensors[J]. Chinese Physics B, 2020, 29(8):
Received: Mar. 17, 2020
Accepted: --
Published Online: Apr. 29, 2021
The Author Email: Zhou Yan (zhouyan@cuhk.edu.cn)