X-ray scintillators are widely used in medical diagnosis, safety inspection, industrial non-destructive detection, and other fields. In the past decade, zero-dimensional (0D) organic-inorganic hybrid metal halides have gradually attracted attention and shown great potential in X-ray imaging due to their excellent physical properties and luminescent properties such as non-deliquescence, high stability, no self-absorption, and high luminescent quantum efficiency. This article will overview the basic detection principles and key detection performance parameters of X-ray scintillators, introduce the research progresses of the most representative 0D manganese-based, tin-based, antimony-based, and copper-based halide scintillators in the field of X-ray imaging, and look forward to the future development direction of these 0D hybrid materials.