To address the challenges of complex process and poor substrate adaptability in current low-dimensional material transfer schemes, a fixed-site transfer method based on flexible polymer film polydimethylsiloxane (PDMS) is proposed in this paper. The deformation of PDMS flexible film is the basis for its close adhesion to different substrates. For different target substrates, only the corresponding substrate micro-adjustment system cover plate need to be replaced, and in combination with the three-dimensional displacement mechanical system, the universal fixed-point transfer of one-dimensional and two-dimensional materials is realized. This method avoid the strict conditions of vacuum adsorption and substrate heating during the transfer process, which effectively reduce the difficulty of the fixed-point transfer of low-dimensional materials and improve the transfer stability and versatility. In addition, this method also enable the construction of homogeneous junctions or other vertical structures of low-dimensional materials, thus greatly improving the structural richness of low-dimensional materials.