In response to the lack of systematic and realistic scenarios in the current wireless communication course, which only focuses on basic theoretical derivation and module function simulation, an orthogonal frequency division multiplexing (OFDM) wireless communication system experiment based on GNURadio software and universal software radio peripheral (USRP) hardware platform is proposed. The experiment includes mastering the basic principles of OFDM, building an OFDM transceiver system, analyzing relevant communication performance, completing the hardware system, and finally conducting real wireless communication tests to achieve real-time video transmission. Through the synergy of software systems and hardware platforms, students can fully understand the basic principles of wireless communication, the use of various communication modules, the architecture of wireless communication systems, and related performance analysis methods. This experiment spans from theoretical foundation to engineering application, from module verification to system implementation, from ideal environment simulation to actual scenario testing, and comprehensively improves engineering literacy.