A subwavelength focal spot can be generated by tightly focused laser beams through lens with large numerical aperture (NA), which may have potential applications in microscopy, photoetching and data storage. The transmittances of tightly focused vortex beams and non-vortex beams through turbid media are experimentally studied. The influences of the NA of objective and the topological charge of vortex beam on the transmittance are investigated in details. The experimental results show that the transmittance is stronger if beam carries spiral phase under the same experimental conditions. Moreover, a larger topological charge and a larger NA can produce a stronger transmittance.