The multi-component ceramics of BaO-SrO-CaO-MgO-Al2O3-2SiO2(BSCMAS) with different molar ratio of Ba,Sr,Ca,Mg were prepared by a conventional solid-state reaction. The fabrication procedure, CMAS corrosion resistance, and microstructures of BSCMAS were investigated. The results show that the multi-component ceramics of Ba0.3Sr0.3Ca0.35Mg0.05Al2Si2O8 (B0.3S0.3C0.35M0.05AS) can form a single-phase solid solution by adjusting the concentration of MgO. The CMAS corrosion of B0.3S0.3C0.35M0.05AS were carried out at 1 250, 1 300 ℃ and 1 350 ℃. The B0.3S0.3C0.35M0.05AS showed better CMAS corrosion resistance than Ba0.5Sr0.5Al2Si2O8. The sluggish diffusion of multi-component cations in B0.3S0.3C0.35M0.05AS leads to suppressing the interdiffusion of Ba—Sr with Ca—Mg, combined with the quick formation of anorthite to block the out-diffusion of Ba and Sr, resulting in the improved CMAS corrosion resistance of B0.3S0.3C0.35M0.05AS material.