Under the influence of temperature changes, the phase of the CCD sampling signal of a high-resolution remote sensing camera canvary.This canadversely affect the signal-to-noise ratio and dynamic range of the imageand may even cause the image to be displayedabnormally. To solve this problem of temperature-relatedsampling position drift, an adaptive compensation design was developed for the CCD sampling position of a high-resolution remote sensing camera. First, the initial position of the CCD sampling signal was precisely adjusted, and an adaptive compensation circuit was then designed tocontrol the power consumption, which rendered the temperature of each driver chipto be essentially the same. The advantage of this method is that the CCD and sampling signals can be effectively monitored during temperature changes, thus, ensuring the accuracy of the sampling position of the CCD signal and stability of the signal-to-noise ratio of the image. The experiments indicate that with this method, the accuracy of the initial position adjustment of the correlated double-sampling signal improves to less than 0.039 ns. Additionally, the maximum delay of the correlated double-sampling signal in the satellite in-orbit temperature range is 0.46 ns, which ensures high-quality imaging and meets the requirements of space applications.