Journal of Innovative Optical Health Sciences, Volume. 14, Issue 1, 2140009(2021)
Swept source intraoperative OCT angiography
To accurately guide surgical instruments during ophthalmic procedures, some necessary intraoperative depth perception is required, which standard surgical microscopes supply limitedly. Intraoperative optical coherence tomography (iOCT), combining optical coherence tomography (OCT) technology and surgical microscope, enables noninvasive, real-time and highresolution cross-sectional imaging. Currently, though iOCT enables structural imaging, little research has been done on intraoperative angiography. In this work, we presented a swept-source intraoperative OCT angiography (SS-iOCTA) system based on a standard surgical microscope, which provides both structural and angiographic images. The feasibility of the proposed SSiOCTA was confirmed through deep anterior lamellar keratoplasty (DALK) of ex vivo porcine eyes and blood perfusion imaging of in vivo rat cortex. High-resolution intraoperative feedback, including sub-surface structure and angiogram of biological tissue, can be visualized simultaneously with the SS-iOCTA system, which expand the surgeon's capabilities and could be widely used in clinical surgery.
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Ziyi Zhang, Tiepei Zhu, Tongtong Cao, Zhaoyu Gong, Lin Yao, Kaiyuan Liu, Juan Ye, Peng Li. Swept source intraoperative OCT angiography[J]. Journal of Innovative Optical Health Sciences, 2021, 14(1): 2140009
Received: Oct. 13, 2020
Accepted: Dec. 16, 2020
Published Online: Apr. 7, 2021
The Author Email: Li Peng (peng_li@zju.edu.cn)