Acta Optica Sinica, Volume. 42, Issue 10, 1017001(2022)

Terahertz Wave Imaging Detection of Blast-Induced Traumatic Brain Injury of Rats

Yuye Wang1,2、*, Haibin Li1,2, Zelong Wang1,2, Limin Wu1,2, Meilan Ge1,2, Degang Xu1,2, Tunan Chen3, Hua Feng3, and Jianquan Yao1,2
Author Affiliations
  • 1School of Precision Instrument and Opto-Electronics Engineering, The Institute of Laser and Opto-Electronics, Tianjin University, Tianjin 300072, China
  • 2Key Laboratory of Opto-Electronics Information Technology, Ministry of Education, Tianjin University, Tianjin 300072, China
  • 3Department of Neurosurgery, The Southwest Hospital of Army Medical University, Chongqing 400038, China
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    Traumatic brain injury (TBI) caused by shock waves is one of the most common fatal and disabling diseases, and thus the early detection and classification of blast-induced TBI (bTBI) have important clinical significance. In this paper, based on the continuous terahertz wave imaging system, the brain tissues of rats with different degrees of bTBI are detected by the continuous-wave terahertz attenuated total reflection (CW THz-ATR) imaging system, and the THz images of these brain tissues of different levels of trauma are classified and identified by the support vector machine (SVM). The imaging results show that the detection of brain tissues with mild and moderate bTBI can be realized by the THz-ATR imaging technology. Moreover, the identification and classification of THz images of different levels of trauma by SVM can achieve the accuracy of 86.36%. This suggests that THz imaging technology has great potential for the early and precise detection and diagnosis of different degrees of bTBI.

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    Yuye Wang, Haibin Li, Zelong Wang, Limin Wu, Meilan Ge, Degang Xu, Tunan Chen, Hua Feng, Jianquan Yao. Terahertz Wave Imaging Detection of Blast-Induced Traumatic Brain Injury of Rats[J]. Acta Optica Sinica, 2022, 42(10): 1017001

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    Paper Information

    Category: Medical optics and biotechnology

    Received: Oct. 12, 2021

    Accepted: Dec. 6, 2021

    Published Online: May. 10, 2022

    The Author Email: Wang Yuye (yuyewang@tju.edu.cn)

    DOI:10.3788/AOS202242.1017001

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