In order to solve the problems of high cost, long period and difficult updating in the development of satellite payload ground test equipment, the common functions of ground test equipment for satellite payload are analyzed and summarized, and then a solution, which integrates multiple interfaces such as OC instruction interface, RS422 communication interface, motor pulse interface and AD telemetry interface on a PXI board card, is put forward. The design and research of the corresponding software, hardware and the universality has been carried out, and the purpose of improving the portability and integration of the equipment, controlling the cost, shortening the development period, improving the development efficiency and increasing the generality and configurability has been achieved, which indicates that the designed card has a strong practical significance in aerospace engineering.