Using the different dispersion characteristic of the photonic crystal fiber around different zero dispersion wavelength,the photonic crystal fiber optical parametric amplification was researched with twopump lasers around 780 nm and 1550 nm. Near 780 nm,the impacts of zero dispersion wavelength fluctuations on two-pump photonic crystal fiber optical parametric amplification were investigated,and numerical simulations show that the signal gain bandwidth will vary greatly as the zero dispersion wavelength has a very little change. When the wavelength separation between the two pumps decreased,the impacts of zero dispersion wavelength fluctuations on two-pump photonic crystal fiber optical parametric amplification were restrained to a large extent,but the amplifier bandwidth will have some reduction. Based on this principle,the dispersion flattening optical parametric amplification was designed around 1550 nm. With pump power of 10 W,the gain of fiber optical parametric amplification can reach 65 dB in only 5 m photonic crystal fiber,meanwhile the bandwidth reaches 420 nm,and the gain spectrum is very flattened.