Frontiers of Optoelectronics, Volume. 8, Issue 2, 128(2015)

Technology developments and biomedical applications of polarization-sensitive optical coherence tomography

Zhenyang DING, Chia-Pin LIANG, and Yu CHEN*
Author Affiliations
  • Fischell Department of Bioengineering, University of Maryland, College Park, MD 20742, USA
  • show less

    Polarization-sensitive optical coherence tomography (PS-OCT) enables depth-resolved mapping of sample polarization information, such as phase-retardation and optical axis orientation, which is particularly useful when the nano-scale organization of tissue that are difficult to be observed in the intensity images of a regular optical coherence tomography (OCT). In this review, we survey two types of methods and systems of PS-OCT. The first type is PS-OCT with single input polarization state, which contain bulk optics or polarization maintaining fiber (PMF) based systems and single-mode fiber (SMF) based systems. The second type is PS-OCT with two different input polarization states, which contain SMF based systems and PMF based systems, through either time, frequency, or depth multiplexing. In addition, representative biomedical applications using PS-OCT, such as retinal imaging, skin cancer detection, and brain mapping, are demonstrated.

    Tools

    Get Citation

    Copy Citation Text

    Zhenyang DING, Chia-Pin LIANG, Yu CHEN. Technology developments and biomedical applications of polarization-sensitive optical coherence tomography[J]. Frontiers of Optoelectronics, 2015, 8(2): 128

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Category: REVIEW ARTICLE

    Received: Jul. 30, 2014

    Accepted: Sep. 19, 2014

    Published Online: Jan. 7, 2016

    The Author Email: CHEN Yu (yuchen@umd.edu)

    DOI:10.1007/s12200-015-0475-1

    Topics