Using first-principles calculations based on density functional theory, we investigated the adsorption characteristics of SO₂ and CO molecules on ReS₂ material. Our study reveals the following key findings: compared to CO, SO₂ exhibits stronger interactions with ReS₂, resulting in a more compact adsorption geometry and higher adsorption energy. Differential charge density calculations further elucidate the electron transfer process from the ReS₂ surface to SO₂ molecules. This enhanced electronic density rearrangement at the adsorption interface provides a microscopic explanation for the high sensitivity of SO₂ detection. ReS₂ exhibits rapid desorption capabilities for SO₂ and CO at room temperature, making it a suitable sensing material for ambient SO₂ and CO detection. In summary, ReS₂ possesses the potential for use as a gas sensor and adsorbent material, facilitating the design of novel, high-performance technologies for gas pollution detection.