Space control of natural resources is the basic tool for balancing the relationship between ecological protection and economic development. Observing the bottom line of ecological security pattern strictly is of great guiding significance to reconstruct the new pattern of natural resources spatial control with complete system and ecological surplus. Taking Qixia city, an mountainous intensive agricultural area in Jiaodong Peninsula, as a case study area, coupling pattern and process, integrating geographic information method and model, this paper identified the ecological sources from the aspects of ecosystem service function importance and ecological environment sensitivity. Then the basic ecological resistance surface based on land cover and anthropogenic disturbance was revised by the terrain niche index, and the ecological corridors were identified using the minimum cumulative resistance model, so as to construct the ecological security pattern and achieve natural resources zoning control for Qixia city. The results showed that the ecological sources of Qixia city were 627.80 km2, accounting for 31.14% of the total area, mainly distributed in the central eastern, the central southern and the northwestern regions. More than half of the ecological sources were forest land. The key and optimized ecological corridors were 237.19 km and 83.90 km, mostly composed of forest land, mainly distributed in the central eastern, the northwest and the southwest, forming a complete ecological network. Finally, prohibited, restricted, conditional and prioritized construction areas were delineated. This provided method guarantee for precise control of natural resources space.