Chalcogenide glass fibers have attracted great attention in the infrared (IR) sensing fields, such as liquid monitoring, gas checking, biochemical, microbiology and medicine, for their advantages of wide infrared transmission band, resistance to corrosion, devitrification and not sensitive to microwave radiations. We firstly review the research progress of sensors using chalcogenide glass fibers, and then introduce their working principles. The research of chalcogenide glass fibers is reviewed in terms of sensor application. Their development prospects are also discussed.