Spectroscopy and Spectral Analysis, Volume. 31, Issue 8, 2215(2011)
Study on the Estrogen Derivative Marked by CdTe Quantum Dots
Abstract: Water-soluble CdTe quantum dots (QDs) stabilized by thioglycolic acid (TGA) with high quantum yield were synthesized. And the small biomolecule 17β-amino-estradiol was marked successfully by CdTe QDs. The analysis of UV-Vis spectroscopy, fluorescence spectroscopy, infrared spectroscopy and inverted microscope photographs showed that the surface carboxyl of CdTe quantum dots conjugated with the amino of 17β-amino-estradiol through the activation of N-hydroxysuccinimide. 17β-amino-estradiol marked by CdTe QDs successfully provided an experimental basis for new drug screening model.
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ZHONG Wen-ying, ZHANG Cui, XU Guo-feng, YAN Ming, XU Dan-ke. Study on the Estrogen Derivative Marked by CdTe Quantum Dots[J]. Spectroscopy and Spectral Analysis, 2011, 31(8): 2215
Received: Sep. 18, 2010
Accepted: --
Published Online: Aug. 29, 2011
The Author Email: Wen-ying ZHONG (wyzhong@cpu.edu.cn)