In this paper, 0.6%Pr∶CaxSr1-xF2 (x=0, 0.3, 0.5, 0.7, 1.0) and 0.6%Pr, 5%R∶Ca0.5Sr0.5F2 (R=Y, Lu, Gd) crystals were grown by porous crucible temperature gradient technology. The crystal structure, absorption spectra, fluorescence spectra and fluorescence lifetime were systematically analyzed and discussed. Through the analysis of spectral parameters such as absorption cross section, emission cross section, fluorescence lifetime and fluorescence full width at half maximum (FWHM), it is concluded that 0.6%Pr,5%Y∶Ca0.5Sr0.5F2 mixed crystals have the best spectral parameter compared with other doped mixed crystals. The corresponding absorption cross sections at 443 nm and red emission cross sections at 640 nm are 1.63×10-20 and 3.39×10-20 cm2, respectively. The FWHM and fluorescence lifetime are fitted to be 4.50 nm and 42.8 μs, respectively. The spectral parameters have been greatly improved compared with 0.6%Pr∶CaxSr1-xF2 (x=0, 0.3, 0.5, 0.7, 1.0) mixed crystals. All results show that 0.6%Pr,5%Y∶Ca0.5Sr0.5F2 crystals have great potential as gain media for novel Pr3+ doped broadband laser material.