In order to calibrate the wave aberration caused by large aperture mirror in high resolution space camera, a deformable mirror suitable for space environment was designed. The design criterion of deformable mirror used on space camera was discussed, and the structure form of the deformable mirror was determined; the concrete structure and combination of materials were given, and the flexible structure was added. Simulation results show that, its RMS value is 17.2 nm under z axis gravity and only 3.7 nm when temperature is increased by 4℃, its 1st natural frequency is 1 015 Hz, and after active flattening, the reflecting surface under these simulated space conditions can be corrected to approximate standard plane; it can accurately fit the wave elements corresponding to the first 36 Zernike polynomials, and the residual errors are small. This deformable mirror not only has good mechanical properties and thermal stability, but also can guarantee the aberration correction ability, which meets the application requirement of space camera.