The Pancharatnam phase properties of two coupling-atoms and a single-mode squeezed state light field in nonlinear Kerr medium were studied. Selecting proper initial conditions to solve the Schrdinger equation by the rotating wave approximation, and the Pancharatnam phase specific form was obtained. The results show that the two coupling-atoms’ initial states are in any form, the Pancharatnam phase frequency increases when the interaction strength between atoms and light field, and the dipole-dipole coupling strength between two atoms or the Kerr medium’s nonlinearity increases. The Pancharatnam phase evolution shows obvious trend of oscillating and rising(or fall) when the initial state is that two atoms are both in the excited states. As the growth of the Kerr medium’nonlinearity, the Pancharatnam phase evolution becomes disordered when the initial state is that just one atom is in excited state.