Frontiers of Optoelectronics, Volume. 2, Issue 2, 141(2009)

Differential absorption optical coherence tomography with strong absorption contrast agents of gold nanorods

Ming WEI, Jun QIAN, Qiuqiang ZHAN, Fuhong CAI, Arash GHARIBI, and Sailing HE*
Author Affiliations
  • Centre for Optical and Electromagnetic Research, Joint Research Center of Photonics of the Royal Institute of Technology (Sweden) and Zhejiang University, Zhejiang University, Hangzhou 310058, China
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    Plasmon-resonant gold nanorods (GNRs) are demonstrated as strong absorption contrast agents for optical coherence tomography (OCT). OCT imaging of tissue phantoms doped with GNRs of different resonant wavelengths and concentrations is studied. To utilize the high absorption property of GNRs, a differential absorption OCT imaging is introduced to retrieve the absorption information of GNRs from conventional backscattered signals. It is shown that the contrast of the OCT image can be enhanced significantly when the plasmon resonant wavelength of the GNRs matches the central wavelength of the OCT source.

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    Ming WEI, Jun QIAN, Qiuqiang ZHAN, Fuhong CAI, Arash GHARIBI, Sailing HE. Differential absorption optical coherence tomography with strong absorption contrast agents of gold nanorods[J]. Frontiers of Optoelectronics, 2009, 2(2): 141

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    Paper Information

    Received: Oct. 16, 2008

    Accepted: Dec. 3, 2008

    Published Online: Oct. 8, 2012

    The Author Email: HE Sailing (sailing@kth.se)

    DOI:10.1007/s12200-009-0012-1

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