With water as working fluid, the heat transfer performance of different height/width ratio mini-channel radiators with circular cylinder disturbed flow in front of the mini-channels was experimentally studied. It is found that the 4 mm in height mini-channel radiators with circular cylinder disturbed flow can achieve heat dissipation of 3.2×106 W/m2 when surface temperature is 81.7 ℃ and flow rate is 58.2 L/h. The influence of circular cylinder disturbed flow on heat dispersion is unnoticeable when the flow rate is low. However, as the flow rate increasing, it is becoming distinct. The channel with circular cylinder disturbed flow has the best height when the flow rate is fixed, and the effect of circular cylinder disturbed flow is related to flow rate for the same channels. A general empirical formula is proposed to evaluate cooling performance of the radiators with consideration of Nusselt number as a faction of thermal entrance region length, disturbed flow diameter/ length ratio and height/width ratio. This empirical formula can express the heat transfer of similar radiators well.