For the collection of human health data, which requires multi-parameter and flexible safety sensor, this paper proposes to use the flexible sensor based on fiber Bragg grating(FBG) to detect the temperature, pressure and motion state of the human body. The effects of temperature and pressure on the drift of FBG reflection wavelength and the influence of pressure on the optical power of the fiber are theoretically analyzed, the temperature sensing model, pressure sensing model and human motion model are established. Sensors based on flexible substrates have improved performance in both temperature sensing and pressure sensing. Finally, the flexible base grating sensor is used to monitor the temperature, pressure and motion state of the human body.