A novel quad-band hybrid miniaturized antenna based on Asymmetric Coplanar Waveguide(ACPW) feeders Composite Left and Right Hand Transmission Line(CLRH-TL) is proposed. The antenna is composed of ACPW connected with ground loading open resonant ring gap and monopole antenna terminal loading CLRH-TL unit. The conventional monopole antenna is mixed with the metamaterial zero-order resonator antenna. The measured results show that the impedance bandwidths of the antenna with the antenna return loss above 10 dB are 1.55~1.65 GHz, 2.4~3.7 GHz, 5.15~5.36 GHz and 5.71~5.89 GHz respectively, which have good radiation characteristics in the passbands. The antenna structure is simple, compact and easy to integrate. It can be used in GPS, WLAN and WiMAX wireless communication systems.