As an important transparent glass ceramic system, ZnOMgOAl2O3SiO2 glass exhibits excellent mechanical and optical properties. Numerous studies have focused on the mechanism of controllable nucleation and crystal growth, but the physical mechanism of the substitution of MgO by ZnO on glass transition and crystallization behavior of aluminosilicate glass is not clear. In this work, the effect of the substitution of MgO by ZnO on the glass transition and crystallization behaviors of xZnO·(11-x)MgO·22Al2O3·67SiO2 (x%=0%, 2.2%, 5.5%, 8.8%, 11.0%, mole fraction) glasses was studied. The results show that the glass transition temperature of studied glasses decreases with the substitution of MgO by ZnO， and it can be ascribed to the decrease of the average bonding strength of the glass network, which is induced by the weaker field strength and shielding effect of an extra electron layer in Zn2+ compared to Mg2+. The crystallization phases transfer from singe mullite to the mixture of mullite and zinc aluminate gahnite due to the addition of ZnO causing the phase separation of aluminosilicate glass. The substitution of MgO by ZnO causes a steeper viscosity curve around crystallization temperature and decreases the crystallization activation energy of the glasses, resulting in the shift of crystallization peaks to lower temperature.